Saturday, October 25, 2008

The Stink in Farts Controls Blood Pressure

Honest to God y'all, this is an actual article that I read this morning:

The Stink in Farts Controls Blood Pressure
by Amelia Thomas
LiveScience Staff - Thu Oct 23, 3:21 pm ET

A smelly rotten-egg gas in farts controls blood pressure in mice, a new study finds. The unpleasant aroma of the gas, called hydrogen sulfide (H2S), can be a little too familiar, as it is expelled by bacteria living in the human colon and eventually makes its way, well, out.

The new research found that cells lining mice's blood vessels naturally make the gas and this action can help keep the rodents' blood pressure low by relaxing the blood vessels to prevent hypertension (high blood pressure). This gas is "no doubt" produced in cells lining human blood vessels too, the researchers said.

"Now that we know hydrogen sulfide's role in regulating blood pressure, it may be possible to design drug therapies that enhance its formation as an alternative to the current methods of treatment for hypertension," said Johns Hopkins neuroscientist Solomon H. Snyder, M.D., a co-author of the study detailed in the Oct. 24th issue of the journal Science.

Snyder and his colleagues compared normal mice to mice that were missing a gene for an enzyme known as CSE, long suspected as being responsible for making hydrogen sulfide. As they measured hydrogen sulfide levels taken from tissues of the CSE-deficient mice, the scientists found that the gas was depleted in the cardiovascular systems of the altered mice. By contrast, normal mice had higher levels of the gas, thereby showing that hydrogen sulfide is naturally made by mammalian tissues using CSE.

Next, the mice were subjected to higher blood pressures comparable to serious hypertension in humans. Scientists had them respond to a chemical called methacholine that relaxes normal blood vessels. The blood vessels of the CSE-lacking mice hardly relaxed, indicating that hydrogen sulfide is a huge contender for regulating blood pressure.

Hydrogen sulfide is the most recently discovered member of a family of gasotransmitters, small molecules inside our bodies with important physiological functions.

This study is the first to reveal that the CSE enzyme that triggers hydrogen sulfide is activated itself in the same way as other enzymes when they trigger their respective gasotransmitter, such as a nitric oxide-forming enzyme that also regulates blood pressure, Dr. Snyder said.

Because gasotransmitters are common in mammals all over the evolutionary tree, these findings on the importance of hydrogen sulfide are thought to have broad applications to human diseases, such as diabetes and neurodegenerative diseases.

The research was supported by grants from the U.S. Public Health Service and the Canadian Institutes of Health Research as well as a Research Scientist Award.

My husband said that this explains why he has High Blood Pressure and I don't ... his don't stink! [I've got news for him, his could knock a buzzard off a poo wagon!!]

Well, I'll get him back. Quick ... someone, pull my finger! [giggle] ♥ ∞


Tea Time With Melody said...

I am definately going to pass this article on to MY husband! hahaha

MuseSwings said...

Raises my blood pressure when the sheets start flapping on his side of the bed.

Sparky ♥ ∞ said...

Tea Time ~ What did your Sweetie say when he read the article? Bet he had some funny comments about this one! :o) ♥ ∞

Hi Muse ~ I'm told that's called a Dutch Oven Fart. [ewwwww]!!! What a weird subject I picked today, 'ey?! ♥ ∞

Janeen said...

I'm laughing so hard I'm gonna pee my pants! Oh this is hilarious!

soulbrush said...

no wonder i have such low blood sugar LOL!

Lavinia said...

A buzzard off a poo wagon? I've never heard that one before, it must be a southern expression since we don't have buzzards up here, I guess its too cold for them. Anyway, its very funny! This post was, carrying as it did, winds of scientific discovery! (so to speak...tee hee!)

Sparky ♥ ∞ said...

Hi Lavinia, Such 'winds' we can do without, true!? The expression is used by Southern Rednecks. Someday I'll have to elaborate on the difference between a Southerner and a Redneck (trust me, there is one). The saying is actually "Knock a buzzard off a s**t wagon" but I try not to talk like that anymore. I do try to pretend to have decorum these days. [giggle] I am proud to say that I've never shot up a stop sign though (another Redneck hobby out here ... sigh!). Yer pal. ♥ ∞